Why Flow Chemistry?

  • Compact
  • Safe
  • Speedy
  • Sustainable
  • Smaller
    Small Footprint

Unlike conventional batch synthesis, flow synthesis enables safe and speedy material production using very compact equipment, which fits chemical manufacturing in line with the SDGs.

Recent References:

  • Flow Chemistry Concept: CSIRO, Merbourne, https://www.youtube.com/watch?v=D-VJy4d7tUY
  • Flow Chemistry: Recent Developments in the Synthesis of Pharmaceutical Products, Org. Process Res. Dev. 2016, 20, 2-25
  • A Perspective on Continuous Flow Chemistry in the Pharmaceutical Industry, Org. Process Res. Dev. 2020, 24, 10, 1802–1813
  • Improved efficiency of photo-induced synthetic reactions enabled by advanced photo flow technologies, Photochem. Photobiol. Sci. 2022, 21 , 761-775.
  • Continuous flow technology-a tool for safer oxidation chemistry, React. Chem. Eng., 2022, 7, 490-550.
  • Towards 4th industrial revolution efficient and sustainable continuous flow manufacturing of active pharmaceutical ingredients, React. Chem. Eng., 2022,7, 214-244
  • Application of reactor engineering concepts in continuous flow chemistry: a review, React. Chem. Eng., 2021,6, 1295-1326

Why Flow?


Photolflow reaction technology

  • C-H functionalization reaction
  • Halogenation reaction
  • Photoredox catalyzed reaction

Thermally controlled flow reaction technology

  • Heat-added reaction
  • Heat-removed reaction
  • Cycloaddition reaction
  • Radical reaction

Immobilized catalyst for flow reaction technology

  • Esterification reaction
  • Hydrogenation reaction
  • C-C bond forming reaction

Flow polymerization technology

  • Living radical polymerization
  • Living anionic polymerization

Gas-liquid two-phase flow reaction technology

  • Carbonylation reaction
  • Oxygen oxidation reaction
  • Chlorination reaction

Continuous flow reaction technology

  • Droplet reaction
  • Gravity separation method
  • Automatic parallel synthesis method