Why Flow Chemistry?

  • Compact
    Compact
  • Safe
    Safe
  • Speedy
    Speedy
  • Sustainable
    Sustinable
  • Smaller
					Footprint
    Small Footprint

Unlike conventional batch synthesis, flow synthesis enables safe and speedy material production using very compact equipment, which fits chemical manufacturing in line with the SDGs.

Recent References:

  • Flow Chemistry Concept: CSIRO, Merbourne, https://www.youtube.com/watch?v=D-VJy4d7tUY
  • Flow Chemistry: Recent Developments in the Synthesis of Pharmaceutical Products, Org. Process Res. Dev. 2016, 20, 2-25
  • A Perspective on Continuous Flow Chemistry in the Pharmaceutical Industry, Org. Process Res. Dev. 2020, 24, 10, 1802–1813
  • Improved efficiency of photo-induced synthetic reactions enabled by advanced photo flow technologies, Photochem. Photobiol. Sci. 2022, 21 , 761-775.
  • Continuous flow technology-a tool for safer oxidation chemistry, React. Chem. Eng., 2022, 7, 490-550.
  • Towards 4th industrial revolution efficient and sustainable continuous flow manufacturing of active pharmaceutical ingredients, React. Chem. Eng., 2022,7, 214-244
  • Application of reactor engineering concepts in continuous flow chemistry: a review, React. Chem. Eng., 2021,6, 1295-1326

Why Flow?

Innovations

Photolflow reaction technology

  • C-H functionalization reaction
  • Halogenation reaction
  • Photoredox catalyzed reaction

Thermally controlled flow reaction technology

  • Heat-added reaction
  • Heat-removed reaction
  • Cycloaddition reaction
  • Radical reaction

Immobilized catalyst for flow reaction technology

  • Esterification reaction
  • Hydrogenation reaction
  • C-C bond forming reaction

Flow polymerization technology

  • Living radical polymerization
  • Living anionic polymerization

Gas-liquid two-phase flow reaction technology

  • Carbonylation reaction
  • Oxygen oxidation reaction
  • Chlorination reaction

Continuous flow reaction technology

  • Droplet reaction
  • Gravity separation method
  • Automatic parallel synthesis method