Precise Flow Controller for Pressurized Gass GFC-1

GFC-1

Reactions using gaseous reagents, such as carbon monoxide, dihydrogen, and dioxygen are frequently used in organic synthesis.  They often require highly pressurized conditions. When the gas/liquid biphasic reaction is carried out in a flow system, MFC (mass flow controller) is necessary to control the flow rate of these gases.  We developed a packaged flow control device, GFC-1, allowing precise pressure control to regulate the flow rates under pressurized conditions.   Customizing the GFC-1 depending on the gas type and flow rate range can be ordered according to the customer’s specifications.  Using GFC-1, the Pd-catalyzed carbonylation, radical carbonylation, and Pd-catalyzed hydrogenation of alkenes were carried out efficiently in a flow regime.